KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1B
All Species:
18.48
Human Site:
Y74
Identified Species:
40.67
UniProt:
P16401
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16401
NP_005313.1
226
22580
Y74
K
A
L
A
A
G
G
Y
D
V
E
K
N
N
S
Chimpanzee
Pan troglodytes
XP_527284
226
22578
Y74
K
A
L
A
A
G
G
Y
D
V
E
K
N
N
S
Rhesus Macaque
Macaca mulatta
P40286
208
22075
Y75
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Dog
Lupus familis
XP_545427
211
21163
Y74
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P43276
223
22558
E74
A
A
G
G
Y
D
V
E
K
N
N
S
R
I
K
Rat
Rattus norvegicus
P15865
219
21969
E74
A
A
A
G
Y
D
V
E
K
N
N
S
R
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
E74
A
A
A
G
Y
D
V
E
K
N
N
S
R
I
K
Chicken
Gallus gallus
P08284
219
22026
V74
L
A
A
G
G
Y
D
V
E
K
N
N
S
R
I
Frog
Xenopus laevis
P06892
210
21355
Y77
K
T
L
A
A
G
G
Y
D
V
D
K
N
N
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
C81
Y
I
T
A
T
Y
K
C
D
A
Q
K
L
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
S84
Q
T
K
G
K
G
A
S
G
S
F
K
V
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
52.2
89.3
N.A.
90.7
82.3
N.A.
76.1
72.5
61
N.A.
N.A.
41
N.A.
N.A.
41.5
Protein Similarity:
100
99.5
63.7
91.1
N.A.
92.4
85.8
N.A.
82.7
76.1
68.5
N.A.
N.A.
50.7
N.A.
N.A.
50.8
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
6.6
N.A.
6.6
6.6
86.6
N.A.
N.A.
20
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
6.6
6.6
N.A.
6.6
20
93.3
N.A.
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
73
28
55
46
19
10
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
28
10
0
55
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
28
10
0
37
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
46
10
37
46
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
28
10
% I
% Lys:
46
0
10
0
10
0
10
0
28
10
0
64
0
0
28
% K
% Leu:
10
0
46
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
28
37
10
46
55
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
28
10
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
10
0
28
10
0
46
% S
% Thr:
0
19
10
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
28
10
0
46
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
28
19
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _